Priemel M, von Domarus C, Klatte To help you et al

Priemel M, von Domarus C, Klatte To help you et al

Limbs mineralization problems and you can nutritional D lack: histomorphometric data of iliac crest bone biopsies and you can distributing twenty five-hydroxyvitamin D from inside the 675 clients. J Bones Miner Res 2010; 25: 305–312.

Zhou Y, Zhao LJ, Xu X mais aussi al. DNA methylation degrees of CYP2R1 and CYP24A1 assume supplement D reaction adaptation. J Steroid Biochem Mol Biol 2014; 144: 207–214.

Ralston SH, Binkley N, Boonen S ainsi que al. Randomized demo from alendronate along with vitamin D3 versus important proper care within the osteoporotic postmenopausal girls which have vitamin D deficit. Calcif Structure Int 2011; 88: 485–494.

Weber K, Kaschig C, Erben RG . 1 Leader-hydroxyvitamin D2 and you will 1 alpha-hydroxyvitamin D3 has actually anabolic consequences to the cortical bones, but cause intracortical restorations on toxic dosage when you look at the police video chat ovariectomized rats. Bone 2004; 35: 704–710.

Li M, Healy DR, Simmons HA mais aussi al. Alfacalcidol regulates cancellous limbs for the ovariectomized mice. J Musculoskelet Neuronal Come together 2003; 3: 39–46.

Procedures with elage, and you may collagen crosslinks when you look at the primate limbs

Orimo H, Shiraki M, Hayashi Y mais aussi al. Results of step one leader-hydroxyvitamin D3 on the lumbar bone nutrient density and you will spinal fractures when you look at the people that have postmenopausal weakening of bones. Calcif Structure Int 1994; 54: 370–376.

Shikari Kushida M, Yamazaki K, Nagai K et al. H. Results of 2 years’ therapy of weakening of bones that have step 1 leader-hydroxy vitamin D3 for the bones mineral density and you will incidence of crack: a beneficial placebo-regulated, double-blind potential study. Endocr J 1996; 43: 211–220.

Nuti R, Bianchi G, Brandi ML et al. Excellence from alfacalcidol compared to the nutritional D as well as calcium within the lumbar bone nutrient density during the postmenopausal weakening of bones. Rheumatol Int 2006; 26: 445–453.

Kubodera N, Tsuji Letter, Uchiyama Y ainsi que al. Yet another energetic nutritional D analog, ED-71, factors rise in limbs mass having preferential outcomes towards bones within the osteoporotic customers. J Mobile Biochem 2003; 88: 286–289.

Abe Yards, Tsuji N, Takahashi F ainsi que al. Overview of the latest clinical pharmacokinetics regarding elin D3 by-product. Jpn Pharmacol Ther 2011; 39: 261–274.

Ritter CS, Brown AJ . Inhibition out of PTH by supplement D analog eldecalcitol was modulated because of the its large affinity for the solution supplement D-joining protein and you can effectiveness metabolism. J Mobile Biochem 2011; 112: 1348–1352.

Kondo S, Takano T, Ono Y ainsi que al. Eldecalcitol decreases osteoporotic cracks by the unique mechanisms. J Steroid Biochem Mol Biol 2015; 148: 232–238.

Harada S, Mizoguchi T, Kobayashi Y et al. Everyday government out of elin D analog, develops bones nutrient density from the inhibiting RANKL expression inside mouse trabecular bones. J Limbs Miner Res 2012; 27: 461–473.

Hayashi Y, Fujita T, Inoue T

Matsumoto T, Ito M, Hayashi Y mais aussi al. A different sort of effective supplement D3 analogue, eldecalcitol, suppress the risk of osteoporotic breaks–a great randomized, active comparator, double-blind investigation. Bones 2011; 49: 605–612.

Matsumoto T, Takano T, Saito H mais aussi al. Vitamin D analogs and you may limbs: preclinical and clinical studies having el; 3: 513.

Sakai An excellent, Ito Meters, Tomomitsu T mais aussi al. Effectiveness out-of joint therapy which have alendronate (ALN) and you may elin D analog, to that out-of concomitant ALN, nutritional D together with calcium procedures in the Japanese patients which have pri; 26: 1193–1202.

Plum Los angeles, Fitzpatrick La, Ma X et al. 2MD, yet another anabolic agent for osteoporosis therapy. Osteoporos Int 2006; 17: 704–715.

Ke HZ, Qi H, Crawford DT ainsi que al. A special supplement D analogue, 2MD, restores trabecular and you will cortical bone mass and you will fuel inside the ovariectomized rats having founded osteopenia. J Limbs Miner Res 2005; 20: 1742–1755.

DeLuca HF, Bedale W, Binkley N ainsi que al. The vitamin D analog 2MD grows bones turnover not BMD into the postmenopausal female having osteopenia: consequence of a 1-year phase 2 double-blind, placebo-managed, randomized clinical trial. J Limbs Miner Res 2011; 26: 538–545.

Tinggalkan Balasan

Alamat email Anda tidak akan dipublikasikan. Ruas yang wajib ditandai *